Peer-reviewed veterinary case report
Multimodality characteristics of multifocal choroid plexus carcinoma with bilateral calvarial defects in a dog.
- Journal:
- Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
- Year:
- 2021
- Authors:
- Hughes, Jonathan R et al.
- Affiliation:
- Queen's Veterinary School Hospital · United Kingdom
- Species:
- dog
Abstract
An 8-year-old male intact miniature poodle presented for blindness, obtundation, tetraparesis, and vestibular signs. Magnetic resonance imaging, radiography, and ultrasound revealed a left piriform lobe lesion, right cerebellar and left brainstem lesions, and hydrocephalus and bilateral calvarial defects. Histopathology confirmed a choroid plexus carcinoma with meningeal and intraventricular metastases. The calvarial defect did not show evidence of necrosis, osteoclastic resorption, inflammation or neoplastic infiltration, reflecting a quiescent calvarial atrophy or dysplasia. These novel findings supported inclusion of bone atrophy secondary to chronic increased intracranial pressure as a differential diagnosis for large calvarial defects in dogs with choroid plexus carcinoma.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/30892784/