Peer-reviewed veterinary case report
MRI of osteosarcoma metastases in the brain of an old English Sheepdog.
- Journal:
- Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
- Year:
- 2021
- Authors:
- Toni, Cristina et al.
- Affiliation:
- Neurology · United Kingdom
- Species:
- dog
Plain-English summary
A 9-year-old male neutered old English Sheepdog was brought in because he was acting differently, had trouble seeing, and seemed to ignore things around him for about 10 days. An MRI scan of his brain showed multiple unusual spots that looked different from normal brain tissue. After he passed away, a closer examination of his brain confirmed that these spots were cancerous growths that had spread from an osteosarcoma (a type of bone cancer) found in his right upper leg. This case is notable because the specific MRI features of these brain tumors from osteosarcoma in dogs had not been described before.
Abstract
A 9-year-old, male neutered old English Sheepdog was presented for further investigation of altered mentation, impaired vision, and hemineglect syndrome of 10 days duration. An MRI study of the brain revealed multifocal, contrast-enhancing intra-axial lesions that had a stippled hypointense appearance in all sequences but lacked evidence of a strong signal void on T2* images. Histological examination of the brain postmortem confirmed the lesions were metastases arising from an osteosarcoma, which was later identified in the right humerus. To the authors' knowledge, these MRI characteristics of osteosarcoma metastases in the canine brain have not been previously reported.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/30864172/