Peer-reviewed veterinary case report
Molecular Detection and Phylogenetic Analysis of Canine Parvovirus-2 in Dogs
- Journal:
- Indian Journal of Veterinary Sciences & Biotechnology
- Year:
- 2023
- Authors:
- Khadse, Monali Bhagwan et al.
- Species:
- dog
Plain-English summary
Canine Parvovirus (CPV) is a serious virus that can cause severe stomach issues and heart problems in puppies, especially those around 3 to 4 months old. Even though vaccines are available, some young dogs are still at risk due to weak immunity and practices like early weaning in kennels. In a study conducted in Nagpur, India, researchers tested 50 fecal samples from dogs suspected of having CPV-2. They found that 20% of the samples tested positive using a specific antigen test, and 36% were positive with a more detailed PCR test. The genetic analysis showed that the virus was very similar to strains found in other dogs from India and Sri Lanka.
Abstract
Canine Parvovirus (CPV) is a most significant viral disease causing acute haemorrhagic gastroenteritis and myocarditis in puppies at the age of 3-4 months. It causes serious morbidity and mortality, in spite of the effective vaccination. Inadequate immunity and modern practices of early weaning in the kennels have predisposed the young dogs to CPV. In the present study, total 50 fecal samples were collected from dogs suspected for CPV-2 from Nagpur, India and screened by Ubioquick® VET lateral flow assay kit and Polymerase Chain Reaction (PCR) followed by the sequencing and phylogenetic analysis of VP2 gene. Out of 50 samples, 10 (20%) were found positive by antigen detection test, 18 (36%) by Conventional PCR method. Sequence analysis revealed 98-99% homology with sequences of CPV-2b antigenic type reported in dogs from India and Srilanka.
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Search related cases →Original publication: https://doi.org/10.48165/ijvsbt.19.2.10