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Peer-reviewed veterinary case report

MicroPulse™ transscleral cyclophotocoagulation in the equine patient: A case series of four horses.

Journal:
Veterinary ophthalmology
Year:
2025
Authors:
Sturbaum, A M et al.
Affiliation:
Animal Eye Clinic of Spokane · United States
Species:
horse

Plain-English summary

This study looked at a treatment called MicroPulse transscleral cyclophotocoagulation (MP-TSCPC) for horses suffering from glaucoma, which is a condition that increases pressure in the eye. Four horses were treated, and their eye pressure was measured before and after the procedure. While the initial results showed some reduction in eye pressure, many horses still had high pressure afterward, and some experienced complications like corneal ulcers and the need for additional treatments. Overall, this treatment did not work well for most of the horses, suggesting that different approaches may be needed in the future.

Abstract

OBJECTIVE: To describe the clinical application and outcome of MicroPulse™ transscleral cyclophotocoagulation (MP-TSCPC) treatment in horses with glaucoma. ANIMALS STUDIED: Four client-owned horses with primary (n = 2) or secondary (n = 2) glaucoma. METHODS: Horses were treated with MP-TSCPC under standing sedation with a minimum of 30 days of follow-up (range 30-1241 days). Affected eyes were treated with a 31.3% duty cycle and 3000 mW laser power for a total of 180 s. Data collected included signalment, pre- and post-procedure intraocular pressures (IOPs), laser settings, medications, complications, and repeat therapy. RESULTS: Four horses (5 eyes) received at least one treatment with MP-TSCPC. Mean preoperative IOP was 44 mmHg (range 33-49 mmHg). The immediate mean postoperative IOP was 34 mmHg (4 eyes; range 19-55 mmHg). At 1 week, IOP was 38 mmHg (5 eyes; range 21-80 mmHg), at 2 weeks was 40 mmHg (3 eyes, range 17-80 mmHg), at 1 month was 35 mmHg (5 eyes; range 20-50 mmHg), at 3 months was 18 mmHg (2 eyes; range 14-21 mmHg), at 6 months was 35 mmHg (2 eyes; range 30-39 mmHg), and at >300 days was 24 mmHg (3 eyes; range 18-29 mmHg). Complications included corneal ulceration (n = 1 eye), uncontrolled IOP (n = 3 eyes), and need for repeat treatment (n = 2 eyes). CONCLUSIONS: MP-TSCPC used with the above-described settings was unsuccessful in treating the majority of cases. Future studies should be targeted at primary glaucoma cases and with use of alternative laser settings.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/38225805/