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Peer-reviewed veterinary case report

Meningeal carcinomatosis in a dog: magnetic resonance imaging features and pathological correlation.

Journal:
The Journal of small animal practice
Year:
2010
Authors:
Mateo, I et al.
Affiliation:
Resonancia Magn&#xe9 · Spain
Species:
dog

Plain-English summary

A six-year-old mixed-breed dog had been having seizures for four months that didn't get better with medication, and then suddenly got worse, showing signs of central blindness, which means it couldn't see properly. An MRI scan revealed some unusual cyst-like areas and nodules in the space around the brain. A closer look at the brain tissue confirmed a diagnosis of meningeal carcinomatosis, which is a type of cancer affecting the protective layers around the brain. Unfortunately, the treatment options for this condition are limited, and the prognosis is generally poor.

Abstract

A six-year-old cross breed dog was presented with a four-month history of seizure activity, which was unresponsive to anticonvulsive therapy and an acute deterioration in neurological status, evident as central blindness. Cyst-like structures and nodular enhancement within the subarachnoid space were shown on a magnetic resonance image (MRI) scan. Histopathological examination of brain tissue was consistent with meningeal carcinomatosis.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/20137009/