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Peer-reviewed veterinary case report

Mediastinal squamous cell carcinoma and thyroid carcinoma in an aged horse.

Journal:
Journal of the American Veterinary Medical Association
Year:
1990
Authors:
Hovda, L R et al.
Affiliation:
Department of Medical Sciences
Species:
horse

Plain-English summary

An older horse was diagnosed with two types of cancer: one in the area between the lungs (mediastinal squamous cell carcinoma) and another in the thyroid gland (thyroid carcinoma). The horse showed signs like swelling in both thyroid glands, a long-lasting cough, and some difficulty breathing. These cancers weren't treated, and while squamous cell carcinoma is fairly common in horses, finding it in this specific area is unusual, and thyroid cancer is rare in horses. This combination of cancers is uncommon and might be linked to a problem with the horse's immune system.

Abstract

A mediastinal squamous cell carcinoma and thyroid carcinoma were found in an aged horse. Clinical signs consisted of bilateral thyroid gland enlargement, chronic cough, and mild respiratory distress. The neoplasms were not treated. Squamous cell carcinoma is a common neoplasm in horses, but not in the cranial portion of the mediastinum. Thyroid carcinomas in horses are uncommon. This combination of neoplasms is rare and may have been associated with a defect in the immune system.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/2254149/