Luteoma in a Dog: A Case Report

Abstract

Luteoma is a rare ovarian tumor in dogs. The aim of this article is to report the incidence of luteoma, first observed in a female GSD in Greece. A 3-year-old healthy dog was scheduled for ovariohysterectomy (OHE). During surgical exploration, the ovaries were found to be enlarged with cystic structures. Histological examination revealed tumor cells resembling those of the corpus luteum, organized into multiple lobules, and separated by a well-vascularized connective tissue stroma. Immunohistochemistry (IHC) showed strong cytoplasmic positivity for inhibin-α and vimentin, and zero positivity for calretinin. These lesions consist of luteoma, which is a rare benign tumor. Histopathology is the definitive diagnosis and is best treated with complete OHE.