Peer-reviewed veterinary case report
Long-term efficient control of SIV infection in macaques is associated with an intact intestinal barrier.
- Journal:
- Journal of medical primatology
- Year:
- 2017
- Authors:
- Daskalaki, Maria et al.
- Affiliation:
- Leibniz Institute for Primate Research · Germany
Abstract
Hallmarks of SIV infection are early depletion of gut CD4 T cells and diminished intestinal integrity. Comprehensive studies on colon biopsies of SIV-infected macaques efficiently controlling infection revealed that in contrast to viremic and failing controllers, elite controllers show preserved CD4 T cells, and low viral load, apoptosis, and inflammation.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/28748664/