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Peer-reviewed veterinary case report

Leiomyosarcoma of the duodenum in two horses.

Journal:
Journal of comparative pathology
Year:
1990
Authors:
Mair, T S et al.
Affiliation:
Department of Veterinary Medicine · United Kingdom
Species:
horse

Plain-English summary

Two horses that had been experiencing ongoing, occasional belly pain (colic) were examined after they passed away. During the examination, veterinarians found a thickened area in a part of the small intestine called the duodenum. Further testing showed that this thickening was due to a type of tumor called leiomyosarcoma, which is made up of muscle-like cells. This tumor was causing a blockage in their intestines. Unfortunately, both horses had a serious condition that led to their deaths.

Abstract

Two horses affected by chronic, intermittent colic were found, at post-mortem examination, to have localized annular thickening of a segment of the duodenum. Histological examination of the lesion in both cases revealed a tumour composed of bundles of oval or spindle-shaped cells that stained as muscle with van Gieson stain. The histological diagnosis was leiomyosarcoma. The tumour had caused partial bowel obstruction in both horses.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/2312796/