Peer-reviewed veterinary case report
Labyrinthitis secondary to experimental otitis media.
- Journal:
- American journal of otolaryngology
- Year:
- 2005
- Authors:
- Trinidad, Almudena et al.
- Affiliation:
- Department of Oto-Rhino-Laryngology · Spain
- Species:
- rodent
Abstract
PURPOSE: Analysis of labyrinthitis in a model of otitis media. MATERIALS AND METHODS: Morphologic study in 20 Wistar rats in which otitis media was induced by transbullar inoculation of Pseudomonas aeruginosa with obstruction of the eustachian tube. RESULTS: Seventy percent of rats showed vestibular signs. Histologic changes ranged from nonaffected labyrinths to suppurative labyrinthitis. CONCLUSIONS: Dissemination of infection probably occurs through round window membrane. A thinner round window membrane typical of rodents would be the reason for a more severe clinical and morphologic picture in rats when compared to human beings.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/15991087/