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Peer-reviewed veterinary case report

Jejunal intussusception associated with lymphoma in a horse.

Journal:
The Journal of veterinary medical science
Year:
2013
Authors:
Matsuda, Kazuya et al.
Affiliation:
Department of Veterinary Pathology · Japan
Species:
horse

Plain-English summary

A 2-year-old Thoroughbred horse suddenly developed colitis, which is inflammation of the intestines. During surgery, the vets found a part of the intestine that had folded into itself, and they discovered a mass that was diagnosed as diffuse large B-cell lymphoma, a type of cancer, which had spread to nearby lymph nodes. The location of the mass suggested that it caused the intestine to fold in on itself, leading to the problem. This case is notable because it's the first time such a condition has been reported in horses. The treatment involved surgery to remove the affected part of the intestine, but the outcome regarding the horse's recovery isn't specified.

Abstract

A 2-year-old Thoroughbred horse presented with acute onset of colitis, and the intussuscepted jejunum was surgically resected. A transmural mass protruding into the lumen was found at the leading edge of the intussusceptum. Based on histological and immunohistochemical examinations, the mass was diagnosed as diffuse large B-cell lymphoma with metastasis to the mesenteric lymph nodes. Anatomical localization of the mass in the intussusception and absence of other obvious underlying diseases indicated that the intussusception had occurred in association with the mass. To our knowledge, this case is the first report of equine intussusception associated with focal intestinal lymphoma.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/23629018/