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Peer-reviewed veterinary case report

Intraepidermal animal-type melanoma.

Journal:
International journal of dermatology
Year:
2006
Authors:
Punjabi, S et al.
Affiliation:
Department of Dermatology · United Kingdom
Species:
horse

Plain-English summary

Animal-type melanoma is a rare kind of skin cancer that can occur in humans, and it looks similar to melanomas found in white or gray horses. These tumors usually grow in the skin and are made up of darkly pigmented cells that are somewhat unusual in appearance but do not divide rapidly. Most people diagnosed with this type of melanoma are under 30 years old, and the outlook for recovery is generally better compared to other more common types of melanoma of the same size. This report describes the first known case of animal-type melanoma that was found at an early stage.

Abstract

Animal-type melanoma is a rare variant of melanoma in humans.1 Its name is derived from its histological appearance, which is similar to that described in melanomas occurring in white or gray horses.2 All tumors are dermally located, and characterized by a proliferation of deeply pigmented elongated or rounded cells, showing moderate atypia and a low mitotic rate. In some tumors, secondary infiltration of the epidermis has been noted. More than half of the patients are younger than 30 years, and prognosis seems to be much better than that expected for a superficial spreading or nodular melanoma of the same size. We report the first case of animal-type melanoma in situ.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/16911384/