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Peer-reviewed veterinary case report

Infectious Canine Hepatitis in a Brown Bear ( Ursus arctos horribilis) from Alaska, USA.

Journal:
Journal of wildlife diseases
Year:
2018
Authors:
Knowles, Susan et al.
Affiliation:
1 US Geological Survey · United States
Species:
dog

Abstract

We diagnosed infectious canine hepatitis in a free-ranging brown bear ( Ursus arctos horribilis) cub from Alaska, US, found dead in October 2015. Intranuclear inclusion bodies were present in hepatocytes, and immunohistochemistry showed reactivity to adenoviral antigens. Sequencing of the hexon protein of adenovirus showed 100% identity to canine adenovirus 1.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/29498898/