Impact of exercise on anthropometric outcomes in children and adolescents with overweight or obesity: a systematic review and meta-analysis based on 113 randomized controlled trials worldwide.

Abstract

<h4>Background</h4>At present, the situation of overweight and obesity among children and adolescents around the world is dire. Developing exercise programs for this population is important, based on the vast evidence available, to halt the global rise in childhood and adolescent obesity.<h4>Method</h4>Five databases including PubMed, Embase, Cochrane Library, CNKI, and WanFang were searched, the search period was from March 1, 2010, to March 31, 2024. Randomized controlled trials (RCTs) on the effects of exercise on anthropometric outcomes in children and adolescents with overweight or obesity were retrieved.<h4>Result</h4>A total of 113 RCTs involving 8,514 children and adolescents were included. Meta-analysis results showed that exercise significantly improved body mass index (BMI; mean difference [MD]: -1.16 kg m^-2, P < 0.00001), waist circumference (WC; MD: -2.29 cm, P < 0.00001), body fat percentage (BF%; MD: -2.07%, P < 0.00001) in RCTs on the effects of exercise on anthropometric outcomes among children and adolescents with overweight or obesity were retrieved. The subgroup results showed that national income status was a common source of heterogeneity for BMI (P < 0.0001), WC (P = 0.02), and BF% (P = 0.003).<h4>Conclusion</h4>Exercise improves anthropometric outcomes in children and adolescents who are overweight or obese. Moderate-to-low-intensity aerobic exercise (≥ 3 sessions/week, ≥ 50 min/session, ≥ 12 weeks) as well as programs conducted in middle-income countries are more effective. Future studies need to deepen stratified research through a standardized design, integrate psychological support to improve intervention accuracy and compliance, and accurately implement policies to promote low-cost health interventions and cross-sectoral collaboration.