Peer-reviewed veterinary case report
Imaging diagnosis-malignant peripheral nerve sheath tumor presenting as an intra-axial brain mass in a young dog.
- Journal:
- Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
- Year:
- 2013
- Authors:
- Shihab, Nadia et al.
- Affiliation:
- Department of Veterinary Clinical Sciences · United Kingdom
- Species:
- dog
Plain-English summary
A 3-year-old Labrador retriever started having seizures suddenly. An MRI scan showed a mass in the right side of the brain, specifically in the temporal lobe. The dog underwent surgery to remove the mass, which was found to be a malignant peripheral nerve sheath tumor (a type of cancer that affects the nerves). Although the dog initially recovered, it got worse three months later, leading to the difficult decision of euthanasia. A post-mortem examination confirmed the presence of the tumor, which had spread into the brain, highlighting that this type of tumor, while uncommon, should be considered when diagnosing brain masses in dogs.
Abstract
A 3-year-old Labrador retriever was presented with acute onset seizures. Magnetic resonance imaging demonstrated an intra-axial mass affecting the right temporal lobe of the brain. Surgical resection and histopathological findings were most consistent with a malignant peripheral nerve sheath tumor. After initial recovery, deterioration 3 months post surgery prompted euthanasia. Post-mortem revealed a mass protruding from the ventral surface of the temporal lobe, encroaching upon the optic chiasm and invading the brain. Histopathology findings were again consistent with malignant peripheral nerve sheath tumor. Although rare, this tumor should be included as a possible differential diagnosis for intra-axial brain masses in dogs.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/23363000/