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Peer-reviewed veterinary case report

Hypervirulence of a rough variant of the Mycobacterium abscessus type strain.

Journal:
Infection and immunity
Year:
2007
Authors:
Catherinot, E et al.
Affiliation:
Laboratoire de Microbiologie · France
Species:
rodent

Abstract

We isolated a rough variant of Mycobacterium abscessus CIP 104536T during experimental infection of mice. We show that this variant has lost the ability to produce glycopeptidolipids, is hyperlethal for C57BL/6 mice infected intravenously, and induces a strong tumor necrosis factor-alpha response by murine monocyte-derived macrophages.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/17145951/