Peer-reviewed veterinary case report
Granulosa cell tumor in a mare with a functional contralateral ovary.
- Journal:
- Journal of the American Veterinary Medical Association
- Year:
- 1990
- Authors:
- Hinrichs, K et al.
- Affiliation:
- Department of Medicine · United States
- Species:
- horse
Plain-English summary
A 24-year-old Standardbred mare was found to have a granulosa cell tumor, which is a type of tumor in the ovary. Interestingly, the other ovary was still working normally, producing hormones. The mare was spayed because she was going to be used for jumping and collecting semen from stallions. While it's common for the opposite ovary to shrink and stop functioning in these cases, this mare's other ovary was still active. The findings suggest that not all cases of granulosa cell tumors will show this typical sign.
Abstract
A functional corpus luteum was found in the ovary contralateral to the ovary with a granulosa cell tumor in a 24-year-old Standardbred mare. The mare was ovariectomized because she was to be used as a jump mare for collection of semen from stallions. The blood concentration of progesterone was 2.2 ng/ml, and the luteal tissue progesterone concentration was 6.3 micrograms/mg. Atrophy of the contralateral ovary is one of the major signs used in diagnosis of granulosa cell tumor; however, our findings indicate that the ovary contralateral to a granulosa cell tumor is not invariably nonfunctional.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/2243036/