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Peer-reviewed veterinary case report

Granulomatous polyarthritis caused byin a dog.

Journal:
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
Year:
2020
Authors:
Okada, Kazuki et al.
Affiliation:
North Lab · Japan
Species:
dog

Plain-English summary

A 6-year-old spayed female Toy Poodle weighing 3.5 kg was brought to the vet because she was limping on her left front leg for two days. Two months earlier, X-rays had shown bone damage in her left elbow, which led to the amputation of that leg. Upon examination, the elbow joint showed significant thickening and some erosion of the cartilage. Further tests revealed that her arthritis was caused by a fungal infection, which is unusual in dogs. The treatment for this condition has not been reported before, and the outcome of the treatment was not specified in the study.

Abstract

A 6-y-old, 3.5-kg, spayed female Toy Poodle was presented with left forelimb lameness of 2-d duration. Two months before the initial presentation, radiography showed osteolysis of the medial epicondyle of the left humerus, and the left forelimb was amputated. Grossly, the articular villi of the elbow joint were markedly thickened, and the articular cartilage surfaces of the distal humerus and proximal radius had partial erosion. Histologically, granulomatous arthritis and osteomyelitis characterized by the presence of abundant macrophages containing numerous fungi were observed. ITS and β-tubulin sequences amplified from the isolate from the specimen were 100% and 99% identical to type strain UTHSC D16-145of, respectively. Canine osteoarthritis caused byhas not been reported previously, to our knowledge.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/33000702/