Peer-reviewed veterinary case report
Genotyping of exercise-induced collapse in Labrador retrievers using an allele-specific PCR.
- Journal:
- Veterinary journal (London, England : 1997)
- Year:
- 2012
- Authors:
- Takanosu, Masamine et al.
- Affiliation:
- Nasunogahara Animal Clinic · Japan
- Species:
- dog
Abstract
Exercise-induced collapse (EIC) is an autosomal recessive disorder in Labrador retrievers. In this study, an allele-specific PCR was developed to detect the point mutation G767T in exon 6 of canine DNM1, previously shown to be responsible for canine EIC. Of 133 Labrador retrievers tested in Japan, 6 (4.5%) were homozygous (EIC) and 50 (37.6%) were heterozygous (carriers) for the G767T mutation.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/22104507/