Peer-reviewed veterinary case report
Future research to underpin successful peste des petits ruminants virus (PPRV) eradication.
- Journal:
- The Journal of general virology
- Year:
- 2017
- Authors:
- Baron, Michael D et al.
- Affiliation:
- The Pirbright Institute · United Kingdom
Plain-English summary
Peste des petits ruminants virus (PPRV) is a serious virus that affects small farm animals like sheep and goats, and it's found in many parts of Africa, the Middle East, and Asia. Even though there is an effective and affordable vaccine, the virus keeps spreading, which poses a threat to the livelihoods of communities that depend on these animals for food and income. The Food and Agriculture Organization and the World Organisation for Animal Health are working on a global plan to eliminate this virus, similar to how they successfully dealt with a related virus in the past. However, more research is needed in areas like how the virus spreads, whether it exists in wildlife, and how to create better vaccines and tests. With the help of the global scientific community, there is hope that PPRV can be eradicated.
Abstract
Peste des petits ruminants virus (PPRV) is a significant pathogen of small ruminants and is prevalent in much of Africa, the Near and Middle East and Asia. Despite the availability of an efficacious and cheap live-attenuated vaccine, the virus has continued to spread, with its range stretching from Morocco in the west to China and Mongolia in the east. Some of the world's poorest communities rely on small ruminant farming for subsistence and the continued endemicity of PPRV is a constant threat to their livelihoods. Moreover, PPRV's effects on the world's population are felt broadly across many economic, agricultural and social situations. This far-reaching impact has prompted the Food and Agriculture Organization of the United Nations (FAO) and the World Organisation for Animal Health (OIE) to develop a global strategy for the eradication of this virus and its disease. PPRV is a morbillivirus and, given the experience of these organizations in eradicating the related rinderpest virus, the eradication of PPRV should be feasible. However, there are many critical areas where basic and applied virological research concerning PPRV is lacking. The purpose of this review is to highlight areas where new research could be performed in order to guide and facilitate the eradication programme. These areas include studies on disease transmission and epidemiology, the existence of wildlife reservoirs and the development of next-generation vaccines and diagnostics. With the support of the international virology community, the successful eradication of PPRV can be achieved.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/29022862/