Peer-reviewed veterinary case report
Failure to thrive and life-threatening complications due to inherited selective cobalamin malabsorption effectively managed in a juvenile Australian shepherd dog.
- Journal:
- The Canadian veterinary journal = La revue veterinaire canadienne
- Year:
- 2015
- Authors:
- Gold, Ashley J et al.
- Affiliation:
- Department of Small Animal Clinical Sciences (Gold · United States
- Species:
- dog
Abstract
A juvenile Australian shepherd dog exhibited failure to grow, inappetence, weakness, nonregenerative anemia, neutropenia, and cobalamin deficiency. DNA testing confirmed homozygosity of an amnionless mutation (AMN c.3G > A). Clinical signs resolved with supportive care and parenteral cobalamin supplementation. Inherited selective intestinal cobalamin malabsorption requiring lifelong parenteral supplementation should be considered in Australian shepherds, giant schnauzers, border collies, and beagles that fail to thrive.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/26483576/