Peer-reviewed veterinary case report
Extranodal lymphoma in the cat: prognostic factors and treatment options.
- Journal:
- Journal of feline medicine and surgery
- Year:
- 2013
- Authors:
- Moore, Antony
- Affiliation:
- Veterinary Oncology Consultants Pty Ltd · Australia
- Species:
- cat
Plain-English summary
Most cases of lymphoma in cats occur outside of the lymph nodes, with the gastrointestinal tract being the most common area affected. However, there are many other types of extranodal lymphoma, and this article looks at the factors that can affect the outcome of treatment for these conditions. One challenge is that it's often unclear how to best treat these tumors, especially when they are found in a specific area like the muscles. Currently, veterinarians have to rely on careful assessments of each cat's situation to decide whether localized treatment is enough or if more extensive therapy is needed. Overall, more research is needed to provide clearer guidelines for treating these types of lymphoma in cats.
Abstract
PRACTICAL RELEVANCE: The majority of feline lymphoma is extranodal. While the gastrointestinal (GI) tract is the most commonly affected site, non-GI extranodal lymphomas, which are the focus of this review, account for a large proportion of lymphomas in cats. This article discusses prognostic factors for the most common of these extranodal lymphomas, both in general terms and specifically for individual sites. CLINICAL CHALLENGES: Prognostic factors remain poorly defined for feline lymphoma. Many cats with extranodal lymphoma have stage I disease at an accessible site. A major question for patients with apparently localised extranodal lymphoma is whether the tumour can be treated with localised therapy alone or requires systemic treatment as well. Again there is often no specific information available for a particular site, such as a localised intramuscular lymphoma. Instead, reliance must be placed on careful patient staging, particularly if local therapy alone is planned. EVIDENCE BASE: Until such time as further studies looking at stage, anatomic site, histological grade and immunophenotype are available to assist treatment decision making for an individual cat with extranodal lymphoma, it seems reasonable to draw inferences from other common extranodal sites for which more specific information exists, such as nasal lymphoma.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/23603501/