Peer-reviewed veterinary case report
Experimental diabetes mellitus: oxidative stress and changes in lung structure.
- Journal:
- Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia
- Year:
- 2009
- Authors:
- Forgiarini, Luiz Alberto et al.
- Affiliation:
- Universidade Federal do Rio Grande do Sul
- Species:
- rodent
Abstract
Diabetes mellitus is an endocrine/metabolic disorder characterized by hyperglycemia. Its impact on the respiratory system is characterized by functional changes and alterations in gas exchange. The objective of this study was to evaluate the increase in oxidative stress and the potential damages to the lung structure in an experimental model of streptozotocin-induced diabetes. We conducted histological, biochemical and blood gas analyses in the lungs of diabetic rats. We concluded that the effects of experimental diabetes mellitus include oxidative stress, structural changes in the lung tissue and altered gas exchange.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/19750332/