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Peer-reviewed veterinary case report

Experimental bacteriophage protection against Staphylococcus aureus abscesses in a rabbit model.

Journal:
Antimicrobial agents and chemotherapy
Year:
2005
Authors:
Wills, Quintin F et al.
Affiliation:
Institute of Child Health · United Kingdom
Species:
rabbit

Abstract

In a rabbit model of wound infection caused by Staphylococcus aureus, 2 x 10(9) PFU of staphylococcal phage prevented abscess formation in rabbits when it was injected simultaneously with S. aureus (8 x 10(7) CFU) into the same subcutaneous site. Phage multiplied in the tissues. Phages might be a valuable prophylaxis against staphylococcal infection.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/15728933/