Peer-reviewed veterinary case report
Evolutionary analysis of 3 isolates of Seneca Valley virus from a single pig farm.
- Journal:
- Canadian journal of veterinary research = Revue canadienne de recherche veterinaire
- Year:
- 2022
- Authors:
- Dong, Jianguo et al.
- Affiliation:
- School of Animal Husbandry and Medical Engineering · China
Abstract
Vesicular disease caused by Seneca Valley virus (SVV) has recently emerged throughout China and caused certain industry losses. We used immunofluorescence and western blotting to confirm that 3 new SVV strains (CH-GDSG-2018-1, CH-GDSG-2018-2, and CH-GDSG-2018-3) were from 1 pig farm. Phylogenetic analysis revealed the following: i) all 3 strains belong to USA-GBI29-2015-like clades, ii) CH-GDSG-2018-3 might have diverged from CH-GDSG-2018-1 and CH-GDSG-2018-2, and iii) CH-GDSG-2018-3 is a recombinant of the CHhb17 and HeNKF-1 strains. Virus growth curves showed that CH-GDSG-2018-3 had stronger proliferation ability. Seneca Valley virus has evolved extensively within China and this study has furthered our understanding of SVV epidemiology.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/35388228/