Estimation of the within-herd transmission parameter of bovine leukemia virus.

Abstract

In this study, we estimated the transmission parameter of bovine leukemia virus (BLV) infection within herds by following up the serological status of cattle in beef and dairy herds. Two consecutive serological tests using ELISA were conducted for cattle at four beef breeding farms and nine dairy farms with an interval of 5 months. Assuming that sero-converted animals were newly infected, transmission parameters were estimated using a hierarchical Bayesian Poisson model. All tested herds had at least one positive animal at the first testing, but sero-prevalence considerably varied between herds. It is estimated that 0.62 animals were infected by one infected animal introduced into a fully susceptible population for both beef breeding and dairy farms during the 5-month interval. The 95% credible interval of the transmission parameter for the combined herds was 0.37-0.89 over this period. Asymptomatically infected animals with BLV can become the source of lifelong infection in herds. These estimated transmission parameters indicated that the early removal of infected animals with periodical tests could reduce the dissemination of BLV infection within herds.