Peer-reviewed veterinary case report
Establishment of humanized mice and its application progress in cancer immunotherapy.
- Journal:
- Immunotherapy
- Year:
- 2023
- Authors:
- Ding, Tianlong et al.
- Affiliation:
- The Second Clinical Medical College · China
- Species:
- rodent
Abstract
The current high prevalence of malignant tumors has attracted considerable attention, and treating advanced malignancies is becoming increasingly difficult. Although immunotherapy is a hopeful alternative, it is effective in only a few people. Thus, development of preclinical animal models is needed. Humanized xenotransplantation mouse models can help with selecting treatment protocols, evaluating curative effects and assessing prognosis. This review discusses the establishment of humanized mouse models and their application prospects in cancer immunotherapy to identify tailored therapies for individual patients.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/37096919/