Peer-reviewed veterinary case report
Erythroferrone: the missing link in β-thalassemia?
- Journal:
- Blood
- Year:
- 2015
- Authors:
- Moura, Ivan C & Hermine, Olivier
- Affiliation:
- IMAGINE INSTITUTE.
- Species:
- rodent
Abstract
In this issue of Blood, Kautz et al show that the ablation of the erythroid-derived factor erythroferrone (ERFE), which has been shown to be highly expressed in β-thalassemic mice, restores hepcidin levels and corrects iron overload. However, correction of hepcidin levels in those mice does not improve anemia of β-thalassemia.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/26494918/