Peer-reviewed veterinary case report
Equine viral arteritis in a newborn foal: parallel detection of the virus by immunohistochemistry, polymerase chain reaction and virus isolation.
- Journal:
- Journal of veterinary medicine. B, Infectious diseases and veterinary public health
- Year:
- 2003
- Authors:
- Szeredi, L et al.
- Affiliation:
- Central Veterinary Institute
- Species:
- horse
Plain-English summary
A 4-day-old foal sadly died after experiencing a short illness that included trouble breathing and a fever. During the examination, the veterinarians found significant lung issues, including fluid buildup and inflammation, as well as damage to small blood vessels in various organs, particularly the thymus, which is important for the immune system. They were able to identify the equine arteritis virus in the foal's lungs, kidneys, and spleen using different testing methods. Unfortunately, despite the efforts to diagnose and understand the illness, the foal did not survive.
Abstract
A 4-days-old foal died after a short course of respiratory syndrome and fever. Large areas of the alveoli, bronchioles and bronchi were partly or completely filled by hyaline membranes. Pronounced oedema and mild interstitial pneumonia were present and, in the small muscular arteries, fibrinoid necrosis and vasculitis or perivasculitis could be seen. Vasculitis was found in several other organs, and it was most severe in the thymus. The virus was detected in the lung, kidney and spleen using virus isolation and in the lung and spleen using polymerase chain reaction. The virus was also detected in several organs and cell types using both N protein-specific monoclonal antibody and horseradish peroxidase-labelled equine arteritis virus-specific equine IgG.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/14628997/