Peer-reviewed veterinary case report
Equine herpesvirus-1, non-neurogenic pathotype, in a 9-year-old American Saddlebred with neurological signs.
- Journal:
- The Canadian veterinary journal = La revue veterinaire canadienne
- Year:
- 2009
- Authors:
- Heerkens, Tammy M-J
- Affiliation:
- Ontario Veterinary College · Canada
- Species:
- horse
Plain-English summary
A 9-year-old American Saddlebred horse showed signs of neurological issues, which can happen due to a virus called equine herpesvirus 1 (EHV-1). This virus typically causes respiratory problems and can lead to serious conditions like abortion or neurological disease, but in this case, it was linked to a specific change in the virus's genetic material. Instead of using older methods to identify the virus, veterinarians now use a more advanced test called real-time polymerase chain reaction (RT-PCR), which helps them understand the type and amount of virus present. This new testing method can help manage and control the disease more effectively. The outcome of the treatment was not specified in the abstract.
Abstract
Equine herpesvirus 1 (EHV-1) causes rhinopneumonitis, abortion, and rarely, myeloencephalopathy. The neurovirulence of this virus is due to a point mutation in the DNA polymerase gene. Diagnosis by virus isolation has been replaced by real-time polymerase chain reaction (RT-PCR) assays that can detect strains, viral loads, and states; this may aid in control and management of the disease.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/19436483/