Peer-reviewed veterinary case report
Equine Gastric Squamous Cell Carcinoma in a Friesian Stallion.
- Journal:
- Journal of equine veterinary science
- Year:
- 2022
- Authors:
- Straticò, Paola et al.
- Affiliation:
- Faculty of Veterinary Medicine · Italy
- Species:
- horse
Plain-English summary
A 7-year-old Friesian stallion was brought in because he had been losing weight, eating less than usual, and experiencing repeated fevers. During a procedure to look inside his stomach, the vets found a large, unhealthy mass near the opening of the esophagus. After he passed away, a thorough examination revealed that he had a significant tumor in his stomach, which had spread to other areas like the spleen and liver. Tests showed that a virus called EcPV-2 might be linked to the stomach cancer in horses. Unfortunately, the treatment did not work, and the stallion had a serious form of cancer that had already spread.
Abstract
A 7-year-old Friesian stallion with a history of oesophageal stenosis, weight loss, inappetence, and recurrent hyperthermia was referred for gastroscopy. The stomach mucosa surrounding the oesophageal opening showed a large, necrotic, and ulcerated mass. On post-mortem examination, a very large, cauliflower-like neoplasm was seen, affecting non-glandular gastric mucosa. Nodular lesions were observed, scattered on the omentum, the spleen, and the liver. Microscopic findings allowed the diagnosis of gastric squamous cell carcinoma with abdominal metastasis. Biomolecular investigations demonstrated the presence of EcPV-2 genes in neoplastic lesions, thus supporting the role of EcPV-2 in the ethiology of equine gastric cancer.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/35908598/