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Peer-reviewed veterinary case report

Enterotoxigenic Clostridium perfringens type A necrotic enteritis in a foal.

Journal:
Journal of the American Veterinary Medical Association
Year:
1998
Authors:
Bueschel, D et al.
Affiliation:
Department of Veterinary Science and Microbiology · United States
Species:
horse

Plain-English summary

A foal that was a mix of Thoroughbred and Quarter Horse developed severe intestinal bleeding and sadly died less than two days after being born. Tests showed signs of a Clostridium perfringens type C infection, but further analysis revealed it was actually a type A strain that produces a harmful toxin. This case indicates that this type of bacteria can lead to serious intestinal problems in horses.

Abstract

A Thoroughbred-Quarter Horse crossbred foal developed hemorrhagic enteritis and died < 48 hours after birth. Gross and histologic findings were suggestive of Clostridium perfringens type C infection, and large numbers of C perfringens were isolated from intestinal contents. However, genotyping of isolates indicated that they were enterotoxigenic C perfringens type A, and isolates were found to produce C perfringens enterotoxin in vitro. This case suggests that enterotoxigenic C perfringens type A may cause enteric disease in horses.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/9810388/