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Peer-reviewed veterinary case report

Efficacy of a commercial hydrolysate diet in eight cats suffering from inflammatory bowel disease or adverse reaction to food.

Journal:
Tijdschrift voor diergeneeskunde
Year:
2010
Authors:
Mandigers, Paul J J et al.
Affiliation:
Utrecht University · Netherlands
Species:
cat

Plain-English summary

In a study involving eight cats who were diagnosed with chronic enteropathy, which means they had ongoing vomiting and diarrhea, all cats underwent thorough testing, including a procedure called endoscopy. The tests showed different types of inflammation in their intestines, leading to a diagnosis of inflammatory bowel disease (IBD) or food allergies. The cats were put on a special diet made of hydrolyzed protein, and within 4 to 8 days, their symptoms improved. After two months, they had gained weight, but when they were given their old food again, their symptoms returned. However, switching back to the hydrolyzed diet helped seven of the cats feel better again. This shows that the hydrolyzed protein diet was effective in managing their conditions.

Abstract

Eight of 28 cats presenting with chronic vomiting and/or diarrhoea were diagnosed as suffering from chronic enteropathy. All cats had undergone a complete diagnostic work-up, including endoscopy. Histopathology findings varied from normal, eosinophilic, to lymphoplasmacytic gastroenteritis. On the basis of findings, the cats were diagnosed with inflammatory bowel disease (IBD) or an adverse reaction to food. A hydrolysed protein diet was used as sole therapy, and clinical signs resolved within 4-8 days in all eight cats. After 2 months the cats had gained weight. A challenge trial with their previous diet resulted in recurrence of the clinical signs, which resolved in seven cats when the test diet was reintroduced. We conclude that the hydrolysed protein diet used in the current study was effective in managing these cases.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/20939411/