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Peer-reviewed veterinary case report

Effects of Cadmium on Erythrocytic Parameters

Journal:
Veterinary Clinical Pathology
Year:
1993
Authors:
Waner, Trevor & Gur, Ephraim
Species:
rodent

Abstract

Cadmium was administered via the drinking water to rats at doses of 20 and 200 ppm for 5 weeks in order to elucidate cadmium's primary effect on the erythrocytic parameters. From the results, it appeared that the microcytic hypochromic anemia resulted from a direct effect on erythrocytic hemoglobin due to cadmium administration. It was proposed that the adverse effects on hemoglobin absorption and metabolism play a role in the development of the anemia observed.

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Original publication: https://doi.org/10.1111/j.1939-165x.1993.tb00872.x