Peer-reviewed veterinary case report
Effect of mesenchymal stem cell transplantation on cognitive functions in rats with ischemic stroke.
- Journal:
- Bulletin of experimental biology and medicine
- Year:
- 2006
- Authors:
- Sokolova, I B et al.
- Affiliation:
- Trans-Tekhnologiya Company
- Species:
- rodent
Abstract
The effect of intravenous transplantation of mesenchymal stem cells on the recovery of cognitive functions was studied in Wistar-Kyoto rats after brain stroke induced by occlusion of the middle cerebral artery in the left hemisphere. Analysis 2 and 5 weeks after stroke showed that transplantation of mesenchymal stem cells 3 days after middle cerebral artery occlusion reduced the area of cerebral injury, preserved cognitive functions, and decreased mortality in experimental animals.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/17415450/