Peer-reviewed veterinary case report
Echocardiography-Guided Intramyocardial Injection Method in a Murine Model.
- Journal:
- Methods in molecular biology (Clifton, N.J.)
- Year:
- 2017
- Authors:
- Maeda, Kay et al.
- Affiliation:
- University of Ottawa Heart Institute · Canada
- Species:
- rodent
Abstract
Cardiac regenerative therapy has received attention as a potentially revolutionary approach for treating the damaged heart. The mouse model of myocardial infarction (MI) remains one of the most common tools for the evaluation of such new therapies. Typically, intramyocardial administration of cells or biomaterials in mice is performed by an open-chest surgical procedure, but less invasive delivery methods are becoming available. Echocardiography-based transthoracic myocardial injection is one such minimally invasive approach that can reliably deliver therapeutics to the target site with limited complications and quick recovery for the animal following the procedure. Here, we will describe the method of echocardiography-guided intramyocardial injection in a mouse MI model.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/28229419/