Peer-reviewed veterinary case report
Detection and characterisation of high pathogenicity avian influenza virus (H5N1/H5N8) clade 2.3.4.4b, Hong Kong SAR, China, 2021 to 2024.
- Journal:
- Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
- Year:
- 2025
- Authors:
- Sun, Wanying et al.
- Affiliation:
- School of Public Health · China
- Species:
- bird
Abstract
We isolated three genotypes of highly pathogenic avian influenza virus (HPAIV) clade 2.3.4.4b from wild birds infected with H5N1 (n = 12) and H5N8 (n = 1) in Hong Kong SAR 2021-2024. Viruses from two spoonbills from late 2022 were genetically related to a virus from a human in China. Four tested viruses exhibited variable virulence in mice but were susceptible to approved antivirals. No neutralising antibody was detected in 63 age-stratified human sera, suggesting potential risk should the virus adapt to humans.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/39790075/