Peer-reviewed veterinary case report
Delayed-type hypersensitivity determination.
- Journal:
- Methods in molecular biology (Clifton, N.J.)
- Year:
- 2012
- Authors:
- Gray, Brian M & Eaton, Kathryn A
- Affiliation:
- Department of Microbiology and Immunology · United States
- Species:
- rodent
Abstract
Delayed-type hypersensitivity responses in the skin (in the case of mice, in the foot pad) is used to assess cell-mediated immunity (CMI) in vivo. In the case of CMI to Helicobacter infection, the mice are given an injection of cultured Helicobacter organisms into the hind footpad, and induration is measured at the site of inoculation 24 h after inoculation. Here we describe the methods for assessing delayed-type hypersensitivity in the mouse.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/23015499/