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Peer-reviewed veterinary case report

Dedicated mouse production and husbandry.

Journal:
Methods in molecular biology (Clifton, N.J.)
Year:
2009
Authors:
Vizor, Lucie & Wells, Sara
Affiliation:
Medical Research Council · United Kingdom
Species:
rodent

Abstract

The complexity of mammalian biology, in combination with the ability to manipulate the embryonic genome in mice, has provided specific challenges in terms of mouse breeding, analysis, and husbandry. From the initial planning stage of a project involving the generation of novel, genetically altered mice, it is important to consider a number of potential issues involving the successful establishment and propagation of a transgenic line.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/19504079/