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Peer-reviewed veterinary case report

Cranial cruciate ligament pathophysiology in dogs with cruciate disease: a review.

Journal:
Journal of the American Animal Hospital Association
Year:
2004
Authors:
Hayashi, Kei et al.
Affiliation:
Department of Surgical Sciences · United States
Species:
dog

Plain-English summary

Cruciate disease is a frequent reason why dogs have ongoing limping. In adult dogs, the cranial cruciate ligament (CCL), which helps stabilize the knee, can tear due to gradual wear and tear, even without any obvious injury. This tearing is often linked to inflammation in the joint lining and changes in the ligament's structure. On the other hand, when puppies experience CCL tears, it's usually because of a sudden injury that pulls the ligament away from where it attaches. This review highlights the different causes of CCL issues in dogs of various ages.

Abstract

Cruciate disease is a common cause of chronic lameness in dogs. Midsubstance rupture of the cranial cruciate ligament (CCL) arises from progressive pathological failure, often under conditions of normal loading in adult dogs with CCL instability. A high risk of rupture is associated with inflammation of the synovium and adaptive or degenerative changes in the cells and matrix of the CCL. In contrast, CCL rupture in puppies is usually associated with traumatic injury and avulsion of the CCL from its sites of attachment.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/15347618/