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Peer-reviewed veterinary case report

Congenital heart defects in Arabian horses and the prospects of genetic testing: A review.

Journal:
Equine veterinary journal
Year:
2024
Authors:
Brown, Caitlin et al.
Affiliation:
School of Life and Environmental Sciences · United Kingdom
Species:
horse

Abstract

Congenital heart defects (CHDs) can have profound and potentially life-threatening consequences on horses' health and performance capability. While CHDs are rare in the general horse population, the Arabian breed is disproportionately overrepresented and thus is widely suspected to be genetically predisposed. This review discusses the most common CHDs in Arabian horses, including ventricular septal defect (VSD), tetralogy of Fallot (TOF), patent duct arteriosus (PDA), tricuspid valve atresia (TVA) and atrial septal defect (ASD). This review also explores how future research into the genetic factors that likely underpin many CHDs can revolutionise the way these disorders are managed in Arabian horses.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/38272847/