Peer-reviewed veterinary case report
Congenital fetal rhabdomyoma in a foal.
- Journal:
- Veterinary pathology
- Year:
- 2004
- Authors:
- Meyerholz, D K et al.
- Species:
- horse
Plain-English summary
A young Appaloosa filly was born with a large mass on her neck, measuring about 8 x 12 x 15 cm. This mass was made up of muscle cells arranged in a disorganized way and was not surrounded by a protective capsule. Tests showed that the cells had some characteristics of striated muscle, which is the type of muscle found in the body, and the mass was identified as a rhabdomyoma, a rare benign tumor of muscle. This case is significant because it is the first time a rhabdomyoma resembling the fetal form seen in humans has been reported in a veterinary setting. The outcome of the treatment for this condition is not specified in the abstract.
Abstract
An Appaloosa filly was born with a ventral midline, approximately 8 x 12 x 15 cm subcutaneous cervical mass. The nonencapsulated mass was composed of interlacing and haphazard bundles of spindle cells on moderate to abundant loose myxomatous stroma. A moderate number of cells showed cross striations with minor nuclear variation and a low mitotic rate. Immunohistochemical staining for myoglobin, desmin, actin, vimentin, and S-100 was positive and negative for glial fibrillar antigen and keratin. Rhabdomyomas are rare benign tumors of striated muscle. Rhabdomyomas described previously in the veterinary literature are analogous to the "adult form" of human rhabdomyoma. This is the first report of a veterinary case that 1) clinically and histologically parallels the "fetal form" in human rhabdomyoma and 2) describes a congenital extracardiac rhabdomyoma.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/15347826/