Peer-reviewed veterinary case report
Comparisons of sevoflurane, isoflurane, and halothane anesthesia in spontaneously breathing cats.
- Journal:
- Veterinary surgery : VS
- Year:
- 1996
- Authors:
- Hikasa, Y et al.
- Affiliation:
- Department of Veterinary Surgery · Japan
- Species:
- cat
Plain-English summary
In a study comparing three types of anesthesia—sevoflurane, isoflurane, and halothane—in healthy cats, researchers found that the cats woke up faster when given sevoflurane compared to the other two anesthetics. When nitrous oxide was added, it helped speed up the onset and recovery from halothane anesthesia more than with sevoflurane or isoflurane. Throughout the anesthesia, the cats' heart rates stayed stable, and there were no signs of liver or kidney damage afterward. The overall effects on blood pressure and breathing rates were similar across all three anesthetics, whether nitrous oxide was included or not. In the end, all three anesthetics were found to be safe, with no significant complications.
Abstract
The clinical effects of sevoflurane, isoflurane, and halothane anesthesia with or without nitrous oxide, were compared in healthy, premedicated cats breathing spontaneously during 90 minutes of anesthesia. The effect of nitrous oxide in accelerating the induction of and recovery from anesthesia was more evident for halothane than for sevoflurane or isoflurane. The cats recovered more rapidly from sevoflurane-oxygen than from either halothane- or isoflurane-oxygen. Heart rates did not significantly change during anesthesia with any of the anesthetics. Arterial blood pressures during sevoflurane-oxygen anesthesia were somewhat higher than those with either isoflurane- or halothane-oxygen. There were no significant differences in arterial blood pressures among sevoflurane, isoflurane, and halothane anesthesia when combined with nitrous oxide. The respiration rate during sevoflurane-oxygen was similar to that during halothane-oxygen. There were no significant differences in respiration rate among sevoflurane, isoflurane, and halothane anesthesia when combined with nitrous oxide. The degree of hypercapnia and acidosis during sevoflurane anesthesia was similar to that observed during isoflurane anesthesia and less than during halothane anesthesia. The three anesthetic regimens, with or without nitrous oxide, induced a similar degree of hyperglycemia and hemodilution during anesthesia. Serum biochemical examination did not reveal any hepatic or renal injuries after each anesthesia.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/9012109/