Peer-reviewed veterinary case report
Combination fibrinolytic therapy in the treatment of chronic septic pleuropneumonia in a Thoroughbred gelding.
- Journal:
- Australian veterinary journal
- Year:
- 2012
- Authors:
- Rendle, D I et al.
- Affiliation:
- School of Animal and Veterinary Sciences · United Kingdom
- Species:
- horse
Plain-English summary
This report discusses the treatment of a 3-year-old Thoroughbred gelding with chronic pleuropneumonia, which is a serious lung infection that can cause fluid buildup around the lungs. The horse received two special medications, one that helps break down blood clots and another that helps clear mucus, which were given directly into the chest area early in the treatment. After using these medications, the veterinarians noticed less fluid and less thick material in the horse's chest. This suggests that using these types of treatments could be helpful for certain cases of lung disease in horses. Overall, the treatment appeared to be beneficial for the horse's condition.
Abstract
This report documents the treatment of a case of chronic pleuropneumonia in a 3-year-old Thoroughbred gelding. A recombinant tissue plasminogen activator (tenecteplase) and a recombinant deoxyribonucleic acidase (alphadornase) were infused into the pleural cavity as adjunctive therapy in the early stages of treatment. Instillation of fibrinolytic drugs was associated with a subjective reduction in the amount of fibrin deposition and decreased fluid accumulation within the pleural cavities. Fibrinolytic therapy may be a useful adjunctive therapy in selected cases of intrapleural disease in horses.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/22928684/