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Peer-reviewed veterinary case report

Clinical usefulness of antibodies against Babesia gibsoni detected by ELISA with recombinant P50.

Journal:
The Journal of veterinary medical science
Year:
2006
Authors:
Miyama, Takako et al.
Affiliation:
Faculty of Agriculture · Japan
Species:
dog

Abstract

The clinical usefulness of antibodies against Babesia gibsoni detected by ELISA with recombinant P50 was examined in dogs in an area where B. gibsoni infection was endemic. Only 8 among 14 dogs with acute type B. gibsoni infection without a previous history of infection were positive. This high percentage of false-negative results is thought to be a weak point of ELISA as a diagnostic tool. However, 14 other anemic dogs with a confirmed history of B. gibsoni infection were all positive, thus confirming the higher sensitivity of ELISA in detecting a history of infection.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/17213713/