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Peer-reviewed veterinary case report

Chronic renal failure associated with nephrolithiasis, ureterolithiasis, and renal dysplasia in a 2-year-old quarter horse gelding.

Journal:
Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
Year:
1999
Authors:
Wooldridge, A A et al.
Affiliation:
Department of Veterinary Clinical Sciences · United States
Species:
horse

Plain-English summary

A 2-year-old quarter horse gelding was brought in because he was drinking and urinating a lot. Blood tests showed signs of kidney failure, and an ultrasound revealed that his kidneys were small and oddly shaped, with one kidney having a stone and signs of swelling. A biopsy confirmed that he had severe kidney disease and a condition where the kidneys didn't develop normally. During further examination, two stones were found in the ureter (the tube connecting the kidney to the bladder), and another stone was discovered in the kidney after he passed away. Unfortunately, the treatment did not work, and the horse had end-stage kidney disease.

Abstract

A 2-year-old quarter horse gelding presented for evaluation of polyuria and polydipsia. Azotemia was detected on serum chemistry profile. Small, misshapen, hyperechoic kidneys with decreased corticomedullary demarcation, hydronephrosis, and a right nephrolith were noted ultrasonographically. The diagnosis of end-stage kidney disease and dysplasia was made histopathologically using ultrasound-guided biopsy. Two ureteroliths were found in the right ureter via cystoscopy, and a nephrolith was seen in the right kidney at necropsy. Clinical, ultrasonographic, and pathologic features of equine urolithiasis and renal dysplasia are discussed.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/10463829/