Peer-reviewed veterinary case report
Chronic granulomatous bowel disease in three sibling horses.
- Journal:
- Journal of the American Veterinary Medical Association
- Year:
- 1986
- Authors:
- Sweeney, R W et al.
- Species:
- horse
Plain-English summary
Three sibling Standardbred horses were diagnosed with chronic granulomatous bowel disease, which is a long-term condition affecting the intestines. They showed signs of weight loss, loose stools, and eating less than usual as the disease progressed. Blood tests revealed low protein levels, and their ability to absorb a sugar called xylose was also reduced. When the horses were examined after death, doctors found inflammation in their intestines, lymph nodes, and liver, with one horse showing a specific type of white blood cell infiltration. Unfortunately, no specific cause for the disease could be identified through various tests.
Abstract
Chronic granulomatous bowel disease was diagnosed in 3 sibling Standardbred horses. Clinical signs included weight loss, loose feces, and decreased appetite in the terminal stage of the disease. Abnormal laboratory findings included hypoproteinemia and low xylose absorption. Necropsy revealed granulomatous inflammation of the intestines, mesenteric lymph nodes, and liver. Eosinophilic infiltration of the granulomatous lesions was a prominent finding in one horse. A causative agent was not detected by special histochemical staining or bacteriologic culturing.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/3721973/