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Peer-reviewed veterinary case report

Changes in plasma testosterone levels and semen quality after 3 injections of a GnRH analogue in 3 dogs with spermatogenic dysfunction.

Journal:
The Journal of veterinary medical science
Year:
2005
Authors:
Kawakami, Eiichi et al.
Affiliation:
Department of Reproduction · Japan
Species:
dog

Abstract

Three male Beagles with low plasma luteinizing hormone and testosterone levels and spermatogenic dysfunction (SD-dogs) were given 3 weekly subcutaneous injections of a gonadotropin-releasing hormone analogue (Buserelin; GnRH-AB). The plasma T level of all of the SD-dogs increased and peaked at 4-6 weeks after the first injection. The total number of sperm and the sperm motility of the three SD-dogs increased 5-7 weeks after the first injection. Therefore, the authors concluded that 3 weekly injections of GnRH-AB transiently improves semen quality in some cases of canine spermatogenic dysfunction.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/16397384/