Peer-reviewed veterinary case report
Central diabetes insipidus in a young dog - case report
- Journal:
- Arquivo Brasileiro de Medicina Veterinária e Zootecnia
- Year:
- 2025
- Authors:
- R.R. Ribeiro et al.
- Species:
- dog
Plain-English summary
This case involves an 11-month-old spayed female mixed-breed dog who was drinking and urinating a lot, as well as needing to urinate more frequently at night. Various tests, including blood work and an ultrasound, showed normal results, but her urine was very dilute, which suggested she might have diabetes insipidus (a condition that affects the body's ability to concentrate urine). A special test confirmed this diagnosis, and she was treated with a medication called desmopressin, which is applied in her eyes. After starting treatment, her symptoms improved significantly, and she was drinking much less water, indicating that the treatment worked well.
Abstract
ABSTRACT This work reports a case of an 11-month-old spayed, female mongrel with polyuria, polydipsia, polakiuria and nocturia. Serum biochemistry (alkaline phosphatase, ALT, urea, creatinine, GGT, globulins, triglycerides, cholesterol, total proteins), hemogram, urinalysis and abdominal ultrasound were requested. Blood exams were within the normal range and the urinalysis resulted in urine density of 1.009. Therefore, SDMA, bile acids, bilirubin (total and fractions), urinary protein: creatinine ratio, urinary GGT, Antinuclear Antibodies (ANA), and a new urinalysis were performed. All the measured parameters were within the normal range, except for the urine density of 1.010, suggesting Diabetes Insipidus. The 12-hour water deprivation test associated with desmopressin acetate revealed an increase in urine density to 1.028 and 1.029, one and two hours after administration of the medicine. Treatment was initiated with 3 drops of DDAVP daily in each eye, resulting in a slight improvement in clinical signs, and the dose was increased to 4 drops daily, resulting in the disappearance of the clinical signs and decreased the daily water intake by over 50%.
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Search related cases →Original publication: https://doi.org/10.1590/1678-4162-13310