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Peer-reviewed veterinary case report

Carcinoma in situ within an area of Barrett esophagus in a dog with megaesophagus.

Journal:
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
Year:
2018
Authors:
Kopke, Matthew A et al.
Affiliation:
School of Veterinary Science
Species:
dog

Abstract

A 10-y-old Irish Setter was presented with a history of recurrent episodes of regurgitation and vomiting, with more recent development of tachypnea. Megaesophagus had been diagnosed in the dog 2 y prior to this presentation. A solitary polypoid mass present immediately rostral to the lower esophageal sphincter was biopsied during percutaneous endoscopic gastrostomy tube placement. Barrett esophagus was diagnosed based on the observation of a polypoid mass with intestinal metaplasia that arose from the surrounding esophagus. Histology of the polypoid mass demonstrated squamous-to-columnar metaplasia, hyperplasia, dysplasia, and carcinoma in situ.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/29952726/